Request for regulatory guidance for cancer cachexia intervention trials

Clinical and Surgical Sciences, School of Clinical Sciences and Community Health, Royal Infirmary, University of Edinburgh, Edinburgh, UK; Biochemistry and Molecular Biology of Cancer, Faculty of Biology, University of Barcelona, Barcelona, Spain; Department of Oncology, University of Alberta, Edmonton, Alberta , Canada; Department of Geriatrics, Neurosciences, and Orthopedics, Catholic University of the Sacred Heart, Roma, Italy; Monash University, Australia; University of Warwick, UK; Duke Cancer Institute, Durham, NC , USA; Center for Translational Research in Aging and Longevity, Department of Health and Kinesiology, Texas A&M University, College Station, TX 77843, USA; Center for Stroke Research CSB, Charité – Universitätsmedizin Berlin, Germany; KineMed, Inc., Emeryville, CA 94608, USA; Division of Geriatrics, Duke Medical Center, Durham, NC 27710, USA; Intramural Research Program, National Institute on Aging, NIH, Baltimore, MD 20892, USA; Division of Endocrinology, Diabetes and Metabolism, Center for Translational Research on Inflammatory Diseases, Michael E. DeBakey VA Medical Center, and Baylor College of Medicine, Houston, TX 77030, USA; Albert Einstein College of Medicine, Jacobi Medical Center, Bronx, NY 10461, USA; Department of Oncology, Mayo Clinic, Rochester, MN 55905, USA; Division of Nephrology and Hypertension, University of California Irvine Medical Center, Orange, CA 92868, USA; Department of Cardiology and Department of Research and Education, General Hospital Celje, Celje, Slovenia; Divisions of Geriatric Medicine and Endocrinology, Saint Louis University School of Medicine, St Louis, MO 63103, USA; Department of Clinical Medicine, Sapienza University, Rome, Italy; NIHR Respiratory Biomedical Research Unit at the Royal Brompton and NHS Foundation Trust and Imperial College, London, UK; Department of Medical Sciences, IRCCS San Raffaele Roma. Nutramed Consortium, Italy; NUTRIM School of Nutrition and Translational Research in Metabolism, Department of Respiratory Medicine, Maastricht University Medical Centre, Maastricht, The Netherlands; Oncological Palliative Medicine, Clinic Oncology/Hematology, Department Internal Medicine and Palliative Centre, Cantonal Hospital St.Gallen, Switzerland; Department of Geriatrics, CHU Toulouse, Toulouse, France; Innovative Clinical Trials, Department of Cardiology & Pneumology, University Medical Center Göttingen (UMG), Göttingen, Germany